Cast
| Shameik Moore | Miles Morales |
| Hailee Steinfeld | Gwen Stacey |
| Oscar Isaac | Miguel O'Hara |
| Jake Johnson | Peter B. Parker |
| Issa Rae | Jessica Drew |
| Daniel Kaluuya | Hobart "Hobie" Brown/Spider-Punk |
| Jason Schwartzman | Jonathan Ohnn/The Spot |
| Brian Tyree Henry | Jefferson Davis |
| Luna Lauren Velez | Rio Morales |
| Greta Lee | Lyla |
| Rachel Dratch | Principal |
| Jorma Taccone | Adrian Toomes/The Vulture |
| Shea Whigham | George Stacy |
Crew
| Joaquim Dos Santos | Director |
| Kemp Powers | Director |
| Justin K. Thompson | Director |
| Phil Lord | Producer, Screenwriter |
| Chris Miller | Producer, Screenwriter |
| David Callaham | Screenwriter |
| Amy Pascal | Producer |
| Avi Arad | Producer |
| Christina Steinberg | Producer |
| Bob Persichetti | Executive Producer |
| Peter Ramsey | Executive Producer |
| Rodney Rothman | Executive Producer |
| Aditya Sood | Executive Producer |
| Rebecca Karch | Executive Producer |
| Brian Michael Bendis | Executive Producer |
| Daniel Pemberton | Original Music |